Tuesday, 22 June 2010

More news on CCSVI

Using virtually identical ultrasound techniques to try and reproduce the results by Dr Zamboni, Florian Doepp and colleagues in Berlin have not been able to reproduce the results that put CCSVI on the map. Their results seriously challenge the hypothesis that cerebral venous congestion plays a significant role in the pathogenesis of MS.

What are the implications of these findings for people with MS?

Clearly we need to wait for other studies in this area to clarify the discrepency in the results of these studies. From a clinical perspective we continue to advise against undergoing any interventional therapy until there is clarity on whether or not CCSVI is a real entity or not.

Please click here for an abstract on the study

Sativex for MS-related spasticity

It has been a long haul, but finally another option for people with MS-related spasticity.

Click here for press release

The signficance of this license cannot be under estimated; particularly as the registration study will probably set a precedent for how spasticity studies are done in the future. The Ashworth Scale has had its day and is seriously flawed as an outcome measure. This result can also be viewed as a victory for patient-related outcome measures or PROMS.