Monday, 20 December 2010

A good vitamin D update

THE AUTHORS' CONCLUSIONS ARE SELF-EXPLANATORY: "The current level of evidence for the effectiveness of vitamin D supplementation in the management of people with MS is based on a single randomised control trial with potential high risk of bias, which does not at present allow confident decision-making about the use of Vitamin D in MS. Therefore, until further high quality evidence is available, clinicians may wish to consider relevant MS guidelines on vitamin D supplementation when making decisions about the care of people with multiple sclerosis. Adequately powered, multi-centred RCTs with a focus on clinical as well as immunological and MRI outcomes that are meaningful to people with MS, and are able to provide insight into the benefits of Vitamin D in people with MS, are still required."

Jagannath et al. Cochrane Database Syst Rev. 2010 Dec 8;12:CD008422

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