"An interesting and clear result. The question is will one of the probiotic manufactures give us, or another research group, £1,000,000 to test probiotics vs. placebo in a proof of concept phase 2a study? Or can we run generate sufficient observational data to help generate some interest in this area? It is becoming increasingly clear that 'we are what we eat' and that the contents of our gut influences our immune systems. The question is how do we manipulate the bacterial contents of our gut and if we do will this have a positive effect on immune-mediated disease such as MS? There is only one way to find out to do a randomised, double-blind, controlled trial; this would be 'Good Science' not 'Bad Science'!"