An holistic approach to MS - beta version

I presented a new version of my holistic approach to MS at ECTRIMS; it is inspired by the London Underground map. A lot of people have asked me for the slide which I have distributed.  I would appreciate comments and additions. I am sure I have left things off the slide and want it to be as complete and accurate as possible. Any comments therefore would be much appreciated. 

You can download the file from the following link: an holistic approach to MS