Thursday, 18 October 2012

Natalizumab/Tsyabri vs. CCSVI: Good Science vs. Bad Science

In response to someone's comment re comparing CCSVI to Tysabri or Natalizumab. I have embedded the graph. It is clear the trends are very different; Tysabri/Natalizumab dwarfs that of CCSVI. In epidemiological terms we would say that Tysabri/Natalizumab is endemic, i.e. the number of searches is high, but has reached a stable number of searches. In comparison, CCSVI has peaked and is petering out! To extinction possibly? Who knows only time will tell.


10 comments:

  1. HOh hoh hoh, actually this is fun. I also made search about tysabri and PML, quess which one is higher? Of course tysabri is googled over and over again.. I would google it everyday, cause I'd be so worried about side-effects :)

    - SantaClaus

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  2. Ho Ho Ho is Santa Claus, HOH is Hard of Hearing, but maybe you can read when I say you are not funny :)

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  3. Well, to me it looks as if CCSVI has stablized since april at 18% of its peakvalue whereas Tysabri has stabilized at 12% of its peakvalue.
    Anyhow, try calculating number of Tysabri users vs "Tysabri" searches in google trend. You will come to the conclusion that the number of users are actually inversely proportional to number of serarches. So what does this tell us about CCSVI.

    Nothing.

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  4. Despite the shallow comments being made here by a comically-challenged poster, Google Trends is actually being used by hospitals to track illness. This study://www.nature.com/nature/journal/v457/n7232/full/nature07634.html provided evidence that Google Trends can be used to track influenza. It was discovered that there was a correlation between the amount of influenza-related doctor appointments and the frequency of certain searches, and by using this data they could provide a report of estimated weekly influenza activity, which is helpful for ER staff:
    "Google Helps Emergency Room Docs to Predict Flu Trends": http://healthland.time.com/2012/01/11/google-helps-emergency-room-docs-to-predict-flu-trends/
    "Johns Hopkins Researchers Find Google Flu Trends a Powerful Early Warning System for Emergency Departments": http://www.hopkinsmedicine.org/news/media/releases/_hopkins_researchers_find_google_flu_trends_a_powerful_early_warning_system_for_emergency_departments

    Here's the Google Flu Trends site: http://www.google.org/flutrends/

    There's also a Google Trends site to track dengue: http://www.google.org/denguetrends/intl/en_us/

    @Anonymous 10:32:00 PM: Tysabri was not a internet-driven phenomenon, like CCSVI.

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  5. this site is full of juvenilles in oblivion Why doctors are more dangerous than guns - Health Ranger investigation you tube watch to realise whats really going on WAKE UP

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  6. People don't need to search CCSVI with google, cause info is shared in facebook groups nowadays. I quess there are now CCSVI facebook groups in many countries. People know what is important, but some doctors don't?? What happened to common sense? Circulation in brain not so important?

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  7. wrong CCSVI is on you tube and twitter where theres lots to find and see

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  8. Google Trends is what it is; it is not pretending to be anything else! The fact that Google has >80% of the world's search volume must mean something. It is like all epidemiological tools there will be shortcomings.

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    Replies
    1. I agree. Other databases including groups and forums have lots of activity not picked up by Google.

      Here is just one example (thisisms.com):

      CCSVI Posts
      ▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓▓ 100,073

      Tysabri Posts
      ▓▓ 4,058

      Delete
  9. I check google tysabri + pml quite often, not cause Im big fan of tysabri but worried about this drug. So trends doesnt always mean any positive value, probably everybody understand this.

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