Saturday, 9 March 2013

Overview of MS drugs

Epub: Thöne J, Ellrichmann G. Oral available agents in the treatment of relapsing remitting multiple sclerosis: an overview of merits and culprits. Drug Healthc Patient Saf. 2013;5:37-47. doi: 10.2147/DHPS.S28822. 



This, it is review if you want an overview of oral MS drugs. I only highlight this review, because it is open source so it can be read for free.



30 May 2011
I keep getting asked what is the most efficacious oral DMT? The following table is a summary of the headline results of the phase 3 studies for the 5 oral DMTs: Reduction Reduction Annual Relapse Rate Disability Progression ...

2 comments:

  1. Prof G, can male patients on fingolimod try to start a family? I think women on the drug are advised not to get pregnant?

    ReplyDelete
    Replies
    1. At present there is no reason why males MSers on fingolimod can't have children.

      Both the US and European SPC (summary of product characteristics) mentions anything about this issue. In animal studies fertility was not affected.

      US: http://www.pharma.us.novartis.com/cs/www.pharma.us.novartis.com/product/pi/pdf/gilenya.pdf

      EU: http://www.medicines.org.uk/EMC/medicine/24443/SPC/Gilenya+0.5mg+hard+capsules

      Delete

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