Sunday, 5 May 2013

Unemployment in MSers

Early aggressive treatment in MS (treat-2-target NEDA) should be viewed as prevention; prevention of future disability and hopefully unemployment. #MSBlog #MSResearch

"Another study focusing on the substrate that leads to unemployment in MSers. Not surprising early retirement  a euphemism for losing your job due to MS, was associated with disability, depression, fatigue, poor cognition and poor health-related quality of life. All these factors are associated with disease activity and progressive damage to the central nervous system. Further argument for aggressive early treatment to prevent damage and to prevent the cascade of events that awaits most MSers with active disease. We need to start thinking more about treat-2-target and the need to suppress all disease activity, i.e. NEDA. Only then will we be able to prevent, or reduce the chances of, unemployment."

EpubKrause et al. Employment status in multiple sclerosis: impact of disease-specific and non-disease-specific factors. Mult Scler. 2013 May 1.

BACKGROUND: MS is associated with high rates of early retirement (ER).


OBJECTIVES: A German cohort of MSers and healthy control subjects (HCs) were compared cross-sectionally to investigate disease- and non-disease-specific factors that are associated with employment status (ES) in MS and to identify predictors of ES in MS.

METHODS: A total of 39 ER MSers, 48 employed MSers, and 37 HCs completed a brief neuropsychological battery and questionnaires related to depressive symptoms, fatigue, health-related quality of life (HrQoL) and health locus of control (HLC). Neurological disability was assessed by the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Functional Composite (MSFC).

RESULTS: ER compared with employed MSers scored significantly higher in neurological disability, depressive symptoms and fatigue and significantly lower in cognitive functioning and HrQoL. Further, both groups differed with regard to age, education, disease course and duration but not in HLC. Neurological disability, age and fatigue were identified as significant predictors of ES in MS.

CONCLUSIONS: ES in MS was associated with demographic aspects, neurological and cognitive status, depressive symptoms, fatigue and HrQoL but was not associated with HLC. Findings confirm neurological disability, age and fatigue as independent predictors of ES in MS.


No comments:

Post a Comment

Please note that all comments are moderated and any personal or marketing-related submissions will not be shown.