Tuesday, 11 February 2014

Stems cells-meta analysis

Ardeshiry Lajimi A, Hagh MF, Saki N, Mortaz E, Soleimani M, Rahim F. Feasibility of Cell Therapy in Multiple Sclerosis: A Systematic Review of 83 Studies. Int J Hematol Oncol Stem Cell Res. 2013;7(1):15-33.



Multiple Sclerosis is an inflammatory disease of the central nervous system in which T cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. The recent advances in stem cell therapies may serve as potential treatments for neurological disorders. There are broad types of stem cells such as neural, embryonic, mesenchymal and hematopoietic stem cells with unprecedented hope in treating many debilitating diseases. In this paper we will review the substantial literature regarding experimental and clinical use of these stem cells and possible mechanisms in the treatment of MS. These results may pave the road for the utilization of stem cells for the treatment of MS.


Stems cells are full of promise but have they delivered so far..maybe read and see. To date the cells are largely immunomodulatory and do not hang around for long so not much time to make myelin or nerves. The question is whether the get the endogenous cells to start repair. 

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