Friday, 11 April 2014

CCSVI II? Hormone replacement Hope or Hype

There have been some interesting reports about sex hormone therapy and progressive MS.  Can you get you hands on hormones?

There are always Dogey Docs out there

We know that sex hormones are very effective at controlling MS as before the advent of Tysabri, pregnancy was the most effective treatment against MS and a host of other autoimmune diseases. In the female oestrogen therapies are being investigated for the men testosterone.

Could testosterone affect progression maybe, there have been some promising reports, but there is not sufficient evidence there at the moment. However, look at the graph above and you could easily make a link.....such as EPO (erythpoietin) which may also have neuroprotective potential. 

However as you can see testosterone treatment does many things, some you may want (Swing) and some you may not. With hormone therapy...dose is very important and it is essential therefore that research is done to work out if it really does work, is it safe and what is the correct dose?

Without proper documentation we get nowhere, if every one having CCSVI was in proper register, we would know if there was merit in it.

2 comments:

  1. True, but a patient who doesn't have 10 years or more to wait for studies, may get some benefit even without perfect knowledge. You won't stop people seeking alternate help for an incurable disease any more than you'll stop homeless people eating from trash bins.

    Why not use ms society funds to create simple registries to track outcomes and adverse events when a trend re alternative treatment starts, especially where full trials won't be funded because treatment is not patentable.

    ReplyDelete
    Replies
    1. There is MS registry
      www.ukmsregistry.org www.narcoms.org in us

      Delete

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