Why haven't we cured MS yet?

What would an MS cure look like? #MSBlog #MSResearch

"The following is my talk from the 5th UCLP MS Research Day. I was asked to answer why we haven't cured MS yet. As you can see from the slides the experiment is currently running and is a 15-25 year experiment. Are MSers who are rendered with NEDA by induction therapies (bone marrow transplantation, alemtuzumab, cladribine) cured? It is also important to manage expectations and explain that someone who already has MS, but has acquired disability, is cured they may be left with some disability. A cure will simply stop you getting worse; it is not neuro-restoration. The other point I make is that our current definition of NEDA is too restrictive and we need to include markers that address the part of the iceberg we can't see. I also conclude the talk with the "black swan" and the fact that the autoimmune hypothesis does not explain everything about the epidemiology of MS and that MS  could still be due to a virus."

"For more defining a cure, please read my previous post; NEDA: defining a cure."



CoI: multiple

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