Wednesday, 24 September 2014

Sleep Problems may have different roots

Vitkova M, Gdovinova Z, Rosenberger J, Szilasiova J, Nagyová I, Mikula P, Krokavcova M, Groothoff JW, van Dijk JP. Factors associated with poor sleep quality in patients with multiple sclerosis differ by disease duration. Disabil Health J. 2014;7(4):466-71

BACKGROUND:Sleep disturbance is a common symptom of multiple sclerosis (MS) and knowledge about factors that contribute to poor sleep quality is scarce.
OBJECTIVE:The aim was to explore the differences in the prevalence and determinants of poor sleep quality in a sample of patients with MS with disease duration ≤5 years and >5 years.
METHODS:We collected data from 152 consecutive patients with MS; 66 patients (78% women, averaged 37.35 ± 10.1 years) were in the group with disease duration ≤5 years and 86 patients (73.3% women, averaged 42.10 ± 9.4 years) in the group with disease duration >5 years. Patients filled out the Sleep Quality Index, the Hospital Anxiety and Depression Scale, the Multidimensional Fatigue Inventory, one item of the Incapacity Status Scale regarding bladder problems and one item of the Short Form-36 regarding pain.
RESULTS:The prevalence of poor sleep is significantly higher in patients with longer disease duration (34.8 vs. 51.2%). Anxiety, reduced motivation and mental fatigue (all p < 0.05) were associated with poor sleep quality in patients with disease duration ≤5 years, whereas pain (p < 0.01), depression and mental fatigue (both p < 0.05) were in patients with disease duration >5 years.
CONCLUSION: Sleep problems are present in patients with MS with both short and long disease duration, but these problems are associated with different factors. These should be recognized and managed in addition to the treatment of sleep disorders.



Sleep problems are well recognised in MS and this looks at the causes and indicates that they may have different routes in early MS anxiety is a problem whereas as depression and pain  and morerelevant in late disease. 

6 comments:

  1. I often wonder if you and prof G use speech recognition system to write blog entries - hence phonetic "routes" instead of "roots" in the title? :-)

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  2. Fixed! MD speaks Yorkshire so a big challenge for any speech recognition system!

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  3. eeeeh... could somebody please translate what MouseDoctor is trying to communicate here?

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  4. I've always only needed 6-7 hours sleep, even before MS, this is pretty solid and I usually wake up refreshed and alert. I don't tend to get much anxiety, because I've worked really hard to not worry/get stressed about things I have no control over (and try as much as possible to deal with things I do have control over) well ... :-) :-) until I started reading this blog!!!

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  5. Hi. Got a quick question. I have fibromyalgia and recently my pain management Dr asked me if any family members have m.s. I've moved to completely new area and I'm seeing new dr and specialists. I had to go through history etc. I'm wondering if I should be pushing to go back to neuro.
    Bit of history.... I had lots of yest to rule out parkinsons as I have memory issues as well as pain and a tremor. Parkinsons was ruled out, thankfully. But she mentioned I had extensive lesions in pons and in white matter. She seemed to brush this off and never made any follow up appointment. But my symptoms are worsening. Should I push to be seen again? It's only about 2 and half years ago I had the mri. Thanks

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