Advent calendar-16

We are talking about the stages required for developing drugs from the original concept. The CRO are busy doing the necessary studies to allow for Investigational New Drug filing.

This has to be completed in cell culture and animals before the drug can be used in humans and this may mean making a lot of drug. 

The chemical synthesis route to make a few milligrammes of compound may not be the best when you have to make drugs in the scale of grammes and kilogrammes of drug. So you need to do a bit of chemistry. So you do the chemistry yourself or get a CRO chemists to do this. They have the facilities to do this to GLP (Good laboratory Practice) standards. Pharma have manufacturing facilities
You have to manufacture loads of compound for your studies

CoI. We are developing a treatment for the control of spasticity 

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