Saturday, 11 April 2015

Botox Helps you achieve your goals or control on incontinence

Chartier-Kastler E, Rovner E, Hepp Z, Khalaf K, Ni Q, Chancellor M.Patient-reported goal achievement following onabotulinumtoxinA treatment in patients with neurogenic detrusor overactivity. Neurourol Urodyn. 2015 Apr 6. doi: 10.1002/nau.22757. [Epub ahead of print]

AIMS: To identify the self-reported treatment goals of patients with urinary incontinence (UI) due to neurogenic detrusor overactivity (NDO), determine whether patients achieved their goals following onabotulinumtoxinA treatment, and assess impact  of neurogenic disease (multiple sclerosis or spinal cord injury) and/or clean intermittent catheterization (CIC) on goal achievement.
METHODS: Data from two Phase III studies of onabotulinumtoxinA 200U (n = 227) or placebo (n = 241) in NDO patients (≥14 UI episodes/week; inadequately managed by anticholinergics) were pooled for analysis. At baseline, patients listed their top two qualitative treatment goals, which were distributed into eight subcategories. Six weeks post-treatment, patients rated whether they achieved their goals (5-point Likert scale). The frequency distribution of goals, the proportion of patients who achieved their goals, and goal achievement by etiology and use/non-use of CIC were assessed.
RESULTS: At baseline, the most common goals were "be dry" (37.9%), "reduce other urinary symptoms" (26.4%), and "improve quality of life/sleep/emotions" (21.4%). Significantly higher proportions of onabotulinumtoxinA-treated patients achieved their overall goals versus placebo (62.0% vs. 17.2%; P <  0.001). OnabotulinumtoxinA treatment resulted in higher goal achievement in all goal categories, regardless of etiology. CIC use did not negatively impact patients' overall goal achievement; significantly higher proportions of onabotulinumtoxinA-treated patients versus placebo achieved their goals regardless of baseline catheterization use or de novo CIC during the first 6 weeks of the study.
CONCLUSIONS:The majority of patients with UI due to NDO achieved their self-determined treatment goals following onabotulinumtoxinA 200U therapy, regardless of aetiology or CIC use.

I guess you can read the conclusions if you have continence problems BotoX can help.

I wonder if anything can help me fend of the hundreds of spam comments for cosmetic Botox that arrives as soon as you mention Botox

2 comments:

  1. Re the spammers - try and invent your own spelling of Botox - this works for all of the Viagra spammers and gets their e-mails past the filters

    ReplyDelete
  2. It works and is liberating! I'm happy to talk about my experiences and have written about it. Lovely to no longer need to be preoccupied where the nearest ladies' room might be.

    ReplyDelete

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