Wednesday, 2 March 2016

NewsSpeak: more thinking time

Can we prevent MS? A renewed focus on environmental modifiable risk factors for MS. #NewsSpeak #MSBlog

"Another opportunity to sit, listen and think."


12 comments:

  1. Gavin,
    Is the report of the
    MS Society Prevention Meeting Programme 12 November 2015
    ready and available?

    ReplyDelete
    Replies
    1. the link to
      MS Society Prevention Workshop Report
      Research into preventing MS is a high priority for people with MS. The MS Society prevention workshop brought together around 50 delegates from around the world to discuss the future of research into the prevention of MS.
      https://www.mssociety.org.uk/ms-resources/ms-society-prevention-workshop-report.

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  2. Friday 4th March 11.30am. Stress. A Miller.
    I wish I could be a person listening to that talk. I have quite a bit to discuss on the subject.

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  3. I'm sure I could trawl through the archives and find a similar Conference from a decade ago - same presenters and same subjects. I never smoked and got MS. I'm very slim and got MS. I did get mono as a teenager but there's no vaccine on the horizon for EBV. I always got lots of sun exposure and take Vit D (10000 strength). The real issues are genes (my aunt had MS) and bad luck (timing of EBV infection). Until the researchers can change our genes and eradicate EBV from our bodies these events are a waste of time. My prediction - in ten year's time they'll still be MS conferences covering EBV, vit D, smoking and obesity, and the patient will be no better off.

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    Replies
    1. Have an identical twin ,75% chance they wont get MS...is it really all genes?

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    2. The major gene locus has been known for over 30-40 years but it has not yielded aa treatment yet

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    3. The difference between first generation and the second generation immigrants ie the children of the first generation immigrants indicates environment plays a role too. The environment factors are perhaps modifiable but unless you practise eugenics your genes are more difficult to control.

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    4. Yes. Case in point is Huntington's Disease (HD). I believe they know the exact cause is a mutated gene and if you have it you will develop the disease. Problem is getting a drug through the BBB and correcting the tiny gene in the dna of neurons. I can't imagine with current technology this would be the solution for MS. They still can't cure HD but know the cause.

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    5. Gene editing undergoes a revolution these days - I would not be surprised to see real treatments for conditions governed by one mutaion. I don't think this applies to MS, though.

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  4. I was worried about it caffeine...
    I love a cup of coffee.
    But last year the media reported the results of a US study and another Norwegian study who drink 4 to 6 cups of coffee would have potential neuroprotective effects, because the effects of caffeine in CNS.
    So what's the coffee now?
    One hour the egg and the coffee are alternating between "good guys" and "rogue" health...

    The stress (more emotional than physical) would be a risk factor for triggering the production of noradrenaline, which in turn stimulates immune system to act?
    And how to make the measurement of emotional stress, or other forms of stress, on scientific research?
    Since what is stressful for me may not be for the other...
    Is the stress would not be a consequence of the disease rather than a cause?

    The question is why the attack is against oligodendrocytes specifically?

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    Replies
    1. I think chronic ongoing emotional stress of many kinds would active the immune system.

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    2. Stress is very wearing on the body. A little stress that we can sleep off some people say gives them motivation.

      Moments of joy can cause damage (to heart), on the BBC news this week.
      http://www.bbc.co.uk/news/health-35710232

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