However, it was administered at 20ml/kg twice a day a so that is 0.5ml in a 25g mouse at twice a day, so that is 1ml a day.
The current limit in the UK is 5ml/kg, so this is 4 times the limit and this result is probably a consequence of stress, as mice learn what is coming and twice a day can be stressful and the volume is so big that it will (osmotically=water balance) stress the animal meaning that animals will not get disease.
Put mice next to a building site and the incidence of EAE down, if you live next to a building site, does MS go away?
So more good stuff from the Far East :-(, where it seems pharma are relocating their pre-clinical animal studies to.
It says "All animal experiments were performed in adherence with the National Institutes of Health Guidelines on the Use of Laboratory Animals and approved by the Second Military Medical University Committee on Animal Care".
Did the first committee get canned for actually supporting the ethical use of animals :-(.
Yes, I will get criticized for highlighting such issues.
Pop Science or Plop science?:-(