Wednesday, 20 July 2016

Occurance of Unrinary Problems

Zecca C, Riccitelli GC, Disanto G, Singh A, Digesu GA, Panicari L, Puccini F, Mattioli M, Tubaro A, Gobbi C. [Epub]Urinary incontinence in multiple sclerosis: prevalence, severity and impact on patients' quality of life. EUR J NEUROL. 2016 DOI: 10.1111/ENE.13010.

BACKGROUND AND PURPOSE:Lower urinary tract symptoms (LUTS) including frequent urination, nocturia and urge urinary incontinence negatively impact quality of life. This project aimed at characterizing the prevalence and severity of urinary incontinence in multiple sclerosis (MS) patients and its association with demographic and clinical features.
METHODS:In all, 403 consecutive clinically stable MS patients answered the International Consultation on Incontinence Questionnaire (ICIQ) and the Patient Perception of Bladder Condition (PPBC) questionnaire. Demographic and clinical parameters including the Expanded Disability Status Scale (EDSS) were collected. Statistical analyses were performed using univariate and multivariate linear regression models.
RESULTS: Females represented 72%, relapsing-remitting patients 82%. The mean (SD) disease duration and EDSS were 11.8 (8.6) years and 3.1 (1.9) respectively. Approximately 35% of patients reported urine incontinence. ICIQ scores were positively associated with EDSS, female gender, presence of LUTS therapies and absence of disease modifying treatments (P < 0.001). PPBC scores were positively associated with EDSS and the presence of LUTS therapies (P < 0.001).
DISCUSSION: Urinary incontinence is frequent in MS, prevailing in more disabled and female patients. Currently available LUTS therapies appear insufficient in the treatment of this symptom. The negative impact of urinary incontinence on quality of life is high and requires more attention in clinical management and research.
Bladder problems are common in MS make sure if you have any to talk to your MS team as things can be done to improve the situation.

1 comment:

  1. My urologist prescribed a combo of solifenacin and mergetreq after I failed on solifenacin alone. It has made a big difference, and I now walk around with dry pantsm with no pad to catch drops, There is research to support this combo, your will need your doctor's support to get insurance to pay for this.

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